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TRPV4 channels stimulate random calcium waves in WKY endothelium

En face intact mesenteric artery of a normotensive rat loaded with Cal-520/AM (5 µM, grey). Intracellular Ca   activities were stimulated by perfusion of TRPV4 channel agonist GSK101 (20 nM) after a baseline recording. Raw signals (left, grey) were recorded at 10 Hz and converted to LUT video (right).

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