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Gαq/11 GPCRs drive regenerative IP -mediated IP  release and Ca   wave propagation

En face mesenteric artery stained with Cal520/AM (5 µM, grey) and cIP  (5 μM). Ca   activity was stimulated by localized photolysis of cIP  (yellow circle) after a baseline recording (10 Hz). In the same preparation, the resulting Ca   activity is visualized in green before (control) and in the presence of the Gαq/11 inhibitor YM254890 (1 µM, 30 mins). Scale bar: 50 μm. 

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