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Lee MD, Buckley C, Zhang, X, Louhivuori, L, Uhlen, P, Wilson, C, McCarron, JG, 2022, 'Small-world connectivity dictates collective endothelial cell signaling'. PNAS. DOI: 10.1073/pnas.2118927119


Dr Calum Wilson MEng, EngD

Chancellor's Fellow (Lecturer)

Half engineer, half physiologist, half historian of the Byzantine empire, Calum is a Chancellor's Fellow (lecturer) that never was any good at maths. Calum is interested in understanding how blood vessel function is regulated by mechanical forces. To help him do so he builds specialised microscopes and experimental apparatus, and writes custom analysis software. If he doesn't know how something works, he will disassemble it. Most of the time he will manage to put things back together properly. Calum's work has received several accolades. Notably, he is a two-time recipient of the Journal of Physiology Early Investigator Prize. More recently, Calum was invited to join the Editorial Board of the Journal of Physiology as an Editorial Fellow. 

Everyone else provided details about what they get up to in their spare time, but Calum did not want to lie by pretending he had any.

Calum can be contacted via:



Zhang, X, Buckley, C, Lee, MD, MacDonald, M, Wilson, C, McCarron, JG 2024, 'Increased TRPV4 channel expression enhances and impairs blood vessel function in hypertension'. Biorxiv.

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Buckley, C, Lee, MD, Zhang, X, Wilson, C, McCarron, JG 2024, 'Signalling switches maintain intercellular communication in the vascular endothelium'. British Journal of Pharmacology.


Zhang, X, Lee MD, Buckley, C, Hollenberg, MD, Wilson, C, McCarron, JG 2023, 'Endothelial PAR2 activation evokes resistance artery relaxation'. Journal of Cellular Physiology.

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Wilson, C, Lee MD, Buckley, C, Zhang, X, McCarron, JG 2022, 'Mitochondrial ATP production is required for endothelial cell control of vascular tone'. Function.

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Wilson, C, McCarron, JG, Lee MD, 2022, 'William Bayliss and the enduring fascination of myogenic tone'. The Journal of Physiology. DOI: 10.1113/JP282890

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Lee MD, Buckley C, Zhang, X, Louhivuori, L, Uhlen, P, Wilson, C, McCarron, JG, 2022, 'Small-world connectivity dictates collective endothelial cell signaling'. PNAS. DOI: 10.1073/pnas.2118927119

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McCarron, JG & Wilson, C, 2022, 'The selfish mitochondrion'. Cell Calcium. DOI: 10.1016/j.ceca.2021.102498.

Zhang, X, Lee MD, Buckley C, Wilson, C, McCarron, JG, 2022, 'Mitochondria regulate TRPV4 mediated release of ATP'. British Journal of Pharmacology. DOI: 10.1111/bph.15687


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Journal icon.jpg

Caldwell, ST, O'Byrne, SN, Wilson, C, Cvetko, F, Murphy, MP, McCarron, JG, Hartley, RC, 2021, 'Photoactivated release of membrane impermeant sulfonates inside cells'. Chem Commun. DOI: 10.1039/d0cc07713e

Buckley, C, Zhang, X, Wilson, C, McCarron, JG, 2020, 'Carbenoxolone and 18b-glycyrrhetinic acid inhibit IP3-mediated endothelial cell calcium signalling and depolarise mitochondria'. British Journal of Pharmacology. DOI: 10.1111/bph.15329

Wilson, C, Lee MD, Buckley C, Zhang, X,  McCarron, JG, 2021, 'Mitochondrial ATP production is required for endothelial cell control of vascular tone'. bioRxiv. DOI: 10.1101/2021.09.14.460297


Wilson, C, Zhang, X, Lee, MD, MacDonald, M, Heathcote, HR, Alorfi, NMN, Buckley, C, Dolan, S, McCarron, JG  2019, 'Disrupted endothelial cell heterogeneity and network organization impair vascular function in prediabetic obesity'. Metabolism. DOI: 10.1016/j.metabol.2020.154340


Buckley, C, Wilson, C, McCarron, JG 2019, 'FK506 regulates IP3-evoked Ca2+ release independently of FKBP in endothelial cells'. British Journal of Pharmacology. DOI: 10.1111/bph.14905

Zhang, X, Lee, MD, Wilson, C, McCarron, JG 2019, 'Hydrogen peroxide depolarizes mitochondria and inhibits IP3-evoked Ca2+ release in the endothelium of intact arteries'. Cell Calcium. DOI: 10.1016/j.ceca.2019.102108

Lawton, PF, Buckley, C, Saunter CD, Wilson, C, Corbett AD, Salter PS, McCarron, JG, Girkin JM 2019, 'Multi-plane remote refocusing epifluorescence microscopy to image dynamic Ca2+ events'. Biomedical Optics Express. DOI: 10.1364/BOE.10.005611

Wilson, C, Zhang, X, Buckley, C, Heathcote, H, Lee, MD, McCarron, JG 2019, 'Increased Vascular Contractility in Hypertension Results From Impaired Endothelial Calcium Signaling' Hypertension. DOI: 10.1161/HYPERTENSIONAHA.119.13791

Heathcote, H, Lee, MD, Zhang, X, Wilson, C,  McCarron, JG,(2019). Endothelial TRPV4 channels modulate vascular tone by Ca2+-induced Ca2+ release at IP3 receptors. British Journal of Pharmacology DOI: 10.1111/bph.14762

McCarron, JG, Wilson, C, Heathcote, H, Zhang, X, Buckley, C, and Lee, MD (2019). Heterogeneity and emergent behaviour in the vascular endothelium. Current Opinions in Pharmacology DOI: 10.1016/j.coph.2019.03.008

Lawton, PF, Lee, MD, Saunter, CD, Girkin, JM, McCarron, JG and Wilson, C (2019). VasoTracker, a low-cost and open source pressure myograph system for vascular physiology. Frontiers in Physiology DOI: 10.3389/fphys.2019.00099

Wilson, C, Lee, MD, Heathcote, H, Zhang, X, Buckley, C, Girkin, JM, Saunter, CD, McCarron, JG 2019, 'Mitochondrial ATP production provides long-range control of endothelial inositol trisphosphate–evoked calcium signaling' Journal of Biological Chemistry. DOI: 10.1074/jbc.RA118.005913


Lee, MD, Wilson, C, Saunter, CD, Kennedy, C, Girkin, JM, McCarron, JG, 2018, 'Spatially structured cell populations process multiple sensory signals in parallel in intact vascular endothelium' Science Signaling, vol 11, no. 9. DOI: 10.1126/scisignal.aar4411

McCarron, JG, Saunter, C, Wilson, C, Girkin, JM & Chalmers, S 2018, Mitochondria structure and position in the local control of calcium signals in smooth muscle cells. in M Trebak & S Earley (eds), Signal Transduction and Smooth Muscle.Boca Raton, Florida, pp. 173-190.


McCarron, JG, Lee, MD & Wilson, C 2017, 'The endothelium solves problems that endothelial cells do not know exist' Trends in Pharmacological Sciences, vol 38, no. 4, pp. 322-338. DOI: 10.1016/

Wilson, C, Saunter, CD, Girkin, JM & McCarron, JG 2017, 'Advancing age decreases pressure-sensitive modulation of calcium signaling in the endothelium of intact and pressurized arteries' Journal of Vascular Research, vol 53, no. 5-6, pp. 358–369. DOI: 10.1159/000454811


Wilson, C, Lee, MD & McCarron, JG 2016, 'Acetylcholine released by endothelial cells facilitates flow-mediated dilatation' Journal of Physiology, vol 594, no. 24, pp. 7267-7307. DOI: 10.1113/JP272927

McCarron, J.G., Chalmers, S., Wilson, C. and Sandison, M.E., 2016. Calcium Mobilization via Intracellular Ion Channels, Store Organization and Mitochondria in Smooth Muscle. In Vascular Ion Channels in Physiology and Disease (pp. 233-253). Springer, Cham.

Wilson, C., Saunter, C.D., Girkin, J.M. and McCarron, J.G., 2016. Clusters of specialized detector cells provide sensitive and high fidelity receptor signaling in the intact endothelium. The FASEB Journal, 30(5), pp.2000-2013. 

DOI: 10.1096/fj.201500090


Wilson, C., Saunter, C.D., Girkin, J.M. and McCarron, J.G., 2015. Pressure‐dependent regulation of Ca2+ signalling in the vascular endothelium. The Journal of physiology, 593(24), pp.5231-5253. DOI: 10.1113/JP271157


McCarron, J.G., Wilson, C., Sandison, M.E., Olson, M.L., Girkin, J.M., Saunter, C. and Chalmers, S., 2013. From structure to function: mitochondrial morphology, motion and shaping in vascular smooth muscle. Journal of vascular research, 50(5), pp.357-371. DOI: 10.1159/000353883

McCarron, J.G., Olson, M.L., Wilson, C., Sandison, M.E. and Chalmers, S., 2013. Examining the role of mitochondria in Ca2+ signaling in native vascular smooth muscle. Microcirculation, 20(4), pp.317-329. DOI: 10.1111/micc.12039


Chalmers, S., Saunter, C., Wilson, C., Coats, P., Girkin, J.M. and McCarron, J.G., 2012. Mitochondrial motility and vascular smooth muscle proliferation. Arteriosclerosis, thrombosis, and vascular biology, 32(12), pp.3000-3011. 

DOI: 10.1161/ATVBAHA.112.255174

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